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Pharmaceutical Formulation Comprising Metformin and Repaglinide
Pharmaceutical Formulation Comprising Metformin and Repaglinide
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机译:包含二甲双胍和瑞格列奈的药物制剂
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摘要
The invention is related to a pharmaceutical composition comprising repaglinide in combination with metformin or a salt thereof in unit dosage form wherein a pre-formulation of the repaglinide has a pH independent dissolution profile and a relative humidity of less than about 25% prior to mixing with the metformin or a salt thereof; and optionally one or more pharmaceutically acceptable excipients and to a method for its preparation.
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