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Drug carrier

机译:毒品携带者

摘要

The present invention has an object of providing a drug carrier capable of controlling in vivo pharmacokinetics. The present invention is directed to a drug carrier comprising a molecular assembly having a drug incorporated therein, and the above object can be achieved by a part of the amphiphilic molecules included in the molecular assembly being released from the molecular assembly by an external environmental change. The present invention utilizes a phenomenon that the hydrophilic-hydrophobic balance of the amphiphilic molecules is shifted toward hydrophilicity by an external environmental change and thus the amphiphilic molecules are freed from the molecular assembly.
机译:本发明的目的是提供一种能够控制体内药代动力学的药物载体。本发明涉及一种药物载体,其包括其中掺入有药物的分子组件,并且上述目的可以通过分子组件中包含的两亲分子的一部分由于外部环境变化而从分子组件中释放而实现。本发明利用了这样的现象,即两亲分子的亲水-疏水平衡由于外部环境变化而向亲水性转移,因此两亲分子脱离了分子组装。

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