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LexA-based chemical-inducible gene expression system for use in transgenic animals
LexA-based chemical-inducible gene expression system for use in transgenic animals
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机译:用于转基因动物的基于LexA的化学诱导基因表达系统
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摘要
The present invention relates generally to chemical-inducible system and to methods of use in transgenic animals. More specifically, the present invention relates to a chimeric transcription factor that binds to a ligand and functions in ligand-dependent manner to induce expression of genes of interest under the control of a synthetic operator-promoter sequence. The expression of genes of interest can be tightly controlled by adding or removing the ligand.
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