Nitrile hydration catalyzed by recyclable ruthenium complexes

摘要

A method for hydrating a nitrile derivative to generate an amide derivative is provided. The method includes mixing the nitrile derivative with a ruthenium catalyst complex in an aqueous solution to form a mixture, and reacting the nitrile derivative with water in the aqueous solution and in the presence of the ruthenium catalyst complex to form a reacted mixture comprising the amide derivative. The ruthenium catalyst complex is represented by the following structural formula: RuX₂(L)_n, wherein X is an anionic ligand, L is a bifunctional phosphine ligand, and n is 3 or 4.