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Use of mifepristone and derivatives therefor as Hedgehog protein signaling pathway modulators and applications of same

机译:米非司酮及其衍生物作为刺猬蛋白信号通路调节剂的用途及其应用

摘要

The invention relates to a novel use of compounds having formula (I), including mifepristone (RU 486 or RU 38 486) and the derivative salts thereof, for the preparation of a medicament that can modulate (activate or inhibit) the Hedgehog protein signalling pathway, which is intended for the treatment of pathologies involving a tissue dysfunction linked to deregulation of said pathway.
机译:本发明涉及包括米非司酮(RU 486或RU 38 486)的式(I)化合物及其衍生物盐在制备可调节(激活或抑制)刺猬蛋白信号传导途径的药物中的新用途。 ,其旨在治疗涉及与所述途径的失调有关的组织功能障碍的病理学。

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