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Use of mifepristone and derivatives therefor as Hedgehog protein signaling pathway modulators and applications of same
Use of mifepristone and derivatives therefor as Hedgehog protein signaling pathway modulators and applications of same
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机译:米非司酮及其衍生物作为刺猬蛋白信号通路调节剂的用途及其应用
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摘要
The invention relates to a novel use of compounds having formula (I), including mifepristone (RU 486 or RU 38 486) and the derivative salts thereof, for the preparation of a medicament that can modulate (activate or inhibit) the Hedgehog protein signalling pathway, which is intended for the treatment of pathologies involving a tissue dysfunction linked to deregulation of said pathway.
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