Method for producing optically active cyclopropane carboxylic acid ester compound, asymmetric copper complex, and optically active salicylideneaminoalcohol compound

摘要

A process for producing an optically active cyclopropanecarboxylic acid ester compound represented by the formula (4):; (wherein R⁵, R⁶ and * each represents the same meaning as defined below), comprising reacting a diazoacetic acid ester represented by the formula (2):N₂CHCO₂R⁵  (2)(wherein R⁵ represents an alkyl group having 1 to 15 carbon atoms or the like) with a compound represented by the formula (3):; (wherein R⁶ represents an alkyl group having 1 to 15 carbon atoms or the like), in the presence of an asymmetric copper complex obtained by reacting a copper compound and an optically active salicylideneaminoalcohol compound represented by the formula (1):; (wherein R¹ represents an alkyl group having 1 to 4 carbon atoms or the like, R² represents a hydrogen atom or the like, R³ and R⁴ independently represent a hydrogen atom or the like, and * represents an asymmetric center).