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Therapy of tumors and infectious agents deficient in methylthioadenosine phosphorylase
Therapy of tumors and infectious agents deficient in methylthioadenosine phosphorylase
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机译:甲硫腺苷磷酸化酶缺乏症的肿瘤和传染病的治疗
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摘要
Methods for treating diseases in humans and vertebrate animals are provided using competitive antagonists of cellular metabolites combined with a protective agent for protecting host cells from toxic effects of the drugs. Also provided are kits comprising competitive antagonists and suitable protective agents. In addition, screening methods for identifying competitive antagonists, protective agents and potentiating agents, for use according to the methods of the invention, are provided.
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