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Use of Antibodies or Antibody Fragments or anti CGRP anti CGRP - R to Treat or prevent forms of acute and chronic diarrhea

机译:使用抗体或抗体片段或抗CGRP和CGRP-R来治疗或预防急性和慢性腹泻

摘要

Methods to treat diarrhea in both acute and chronic forms, through the Administration of a therapeutically or prophylactically effective amount of Antibodies and Fragments thereof with the specificity of the Union (peptide CGRP calcitonin gene-related).In particular, the methods to prevent or reduce diarrhea Disorders or treatments that result in elevated levels of CGRP, e.g., in the Gastrointestinal Tract (Colon) associated with diarrhea or inadequate fluid and electrolyte excretion of intestinal or Urinary System.Relates to treatments that use Antibodies and anti CGRP Fragments that are described in the present Union and its Fragments.Claim 1: a method for inhibiting, preventing or treating diarrhea or dysentery and / or to maintain an appropriate level of electrolytes and fluid in the colon of a patient suffering from a condition associated with diarrhea or dysentery, characterized in that it comprises administering a cant DERY effective Antibody anti CGRP, a fragment of an Antibody anti CGRP,A CGRP Receptor Antibody or a fragment of an Antibody against receptor for CGRP.
机译:通过给予治疗或预防有效量的具有Union特异性的抗体及其片段(肽CGRP降钙素基因相关)来治疗急性和慢性形式的腹泻的方法,尤其是预防或减少方法腹泻导致CGRP水平升高的疾病或治疗方法,例如与腹泻相关的胃肠道(结肠)或肠道或泌尿系统的液体和电解质排泄不足。与使用抗体和抗CGRP片段的治疗有关权利要求1:一种用于抑制,预防或治疗腹泻或痢疾和/或在患有腹泻或痢疾的患者结肠中维持适当水平的电解质和液体的方法,其特征在于,其包括施用有效的DERY有效抗体抗CGRP,它是Antibod的片段y抗CGRP,一种CGRP受体抗体或抗CGRP受体的抗体片段。

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