Assay Systems and methods to identify and characterize lipid-lowering drugs

摘要

Methods for the identification and characterization of candidates for Therapeutic use in the treatment of a disease or condition associated with elevated levels of ldl-c, involving a Rodent, Methods to test the effectiveness of an Antibody that specifically binds to proproteu00edna with Vertasa subtilisin / kexina Type 9 (PCSK9) involving a Rodent,As well as a rodent and its use in the identification and profiling of compounds for the Modulation of a disease or condition associated with elevated levels of ldl-c.