首页> 外国专利> Capsules Gelatin / Alginate delayed Release comprising omega-3 fatty acids and methods and Uses of the same, method of Manufacturing, Pharmaceutical composition

Capsules Gelatin / Alginate delayed Release comprising omega-3 fatty acids and methods and Uses of the same, method of Manufacturing, Pharmaceutical composition

机译:包含omega-3脂肪酸的明胶/海藻酸盐缓释胶囊及其方法和用途,制造方法,药物组合物

摘要

Delayed release capsules and Methods for manufacturarlas. The Capsules comprise a capsular Coating comprises a combination of gelatin and Alginate. Where the coating comprises at least a capsular or filling Agent is Encapsulated with at least one Agent, and where the delayed release capsules are selected from soft capsules and Capsules.Claim 1: a delayed Release Capsule, which comprises a Coating comprising a combination of a capsular Gelatin Gelatin is selected between a type and a combination of a Gelatin Type A and a type B Gelatin, in which Gelatin Has a viscosity of less than about 4.2 mpau00d7segundo Bloom and / or a value of less than approximately 290 g; and Alginate in an amount ranging between 0.2% and about 20% in the weight of gelatinWhere the Alginate has a viscosity that varies between approximately 2 and approximately 600 mpau00d7segundo; where the coating comprises at least a capsular or filling Agent is Encapsulated with at least one Agent, and where the delayed Release Capsule is selected from a cu00e1psul To soft and hard Capsule, with the condition that when Alginate, alginate is rich in G,The viscosity of Alginate is not in the range of between approximately 45 and mpau00d7segundo approximately 420 mpau00d7segundo. Claim 2: The delayed Release Capsule according to claim 1, characterized in that the Capsule is selected from a sustained Release Capsule, a capsule controlled release and enteric coated Capsule.Claim 19: The delayed Release Capsule according to claim 1, characterized in that the Alginate was selected from the Potassium Alginate, Sodium Alginate, alginate, Polyethylene glycol and mixtures thereof.Claim: The delayed Release Capsule 20 according to claim 1, characterized in that the Alginate is selected from an Alginate which comprises a high fraction of manuronic acid (a residue rich in Alginate and Alginate m) comprising a fraction elev ADA (Alginate guluronic acid residues rich in g).Call 112: The delayed Release Capsule according to claim 1 or claim 59, characterized in that the Capsule is selected from a Pharmaceutical composition, Nutritional composition, a composition which is useful as a Nutritional Supplement and in Grediente for Diet.Claim: a Composition of 207 / Alginate Gelatin mixture to produce a delayed Release Capsule, which comprises a Coating comprising a combination of a capsular Gelatin Gelatin is selected between a type and a combination of a GE Latin Type A and a type B Gelatin,Where the Gelatin has a viscosity below approximately 4.2 mpau00d7segundo Bloom and / or a value of less than approximately 290 g; and Alginate in an amount ranging between 0.2% and about 20% in the weight of gelatinWhere the Alginate has a viscosity that varies between approximately 2 and approximately 600 mpau00d7segundo mpau00d7segundo; where the coating comprises at least a capsular or filling Agent is Encapsulated with at least one Agent, where the delayed Release Capsule and select entr And a Soft Capsule and a Capsule, on condition thatWhen the Alginate is an Alginate rich in G, the viscosity of Alginate is not in the range of between approximately 45 and mpau00d7segundo approximately 420 mpau00d7segundo.
机译:延迟释放胶囊和制造方法。所述胶囊包含胶囊剂。涂层包含明胶和藻酸盐的组合。包衣包含至少一种胶囊剂或填充剂,其中包封有至少一种试剂,并且其中延迟释放胶囊剂选自软胶囊和胶囊剂。权利要求1:延迟释放胶囊剂,其包含包含以下物质的组合的包衣:胶囊明胶选自A型明胶和B型明胶的类型和组合,其中明胶的粘度小于约4.2mpa / s,或者值小于约290g;藻酸盐的量在明胶重量的0.2%至约20%之间。其中藻酸盐的粘度在约2至约600mpa / s之间变化。其中包衣包含至少一种胶囊剂或填充剂,并用至少一种试剂包封,并且其中延迟释放胶囊选自软胶囊和硬胶囊,条件是当藻酸盐,藻酸盐富含G时,海藻酸盐的粘度不在约45至约420mpa / s之间。权利要求2:根据权利要求1所述的延迟释放胶囊,其特征在于,所述胶囊选自持续释放胶囊,胶囊控释和肠溶衣胶囊。19,根据权利要求1所述的延迟释放胶囊,其特征在于: 2.海藻酸盐选自海藻酸钾,海藻酸钠,海藻酸盐,聚乙二醇及其混合物。2.根据权利要求1所述的延迟释放胶囊20,其特征在于,所述海藻酸盐选自包含高含量的曼陀罗酸的海藻酸盐(编号112:根据权利要求1或权利要求59所述的延迟释放胶囊,其特征在于,所述胶囊选自药物组合物,所述富含海藻酸盐的残基和富含海藻酸盐的m)包含分数elev ADA(富含g的海藻酸古洛糖醛酸残基)。 ,营养组合物,可用作营养补充剂和在Grediente中用于饮食的组合物。声明:207 /海藻酸钠凝胶的组合物锡混合物以产生延迟释放胶囊,其包含包衣,所述包衣包含胶囊明胶的组合,而明胶选自GE拉丁A型和B型明胶的组合和组合,其中明胶的粘度低于约4.2 mpa u00d7segundo Bloom和/或小于约290 g的值;藻酸盐的粘度在明胶重量的0.2%至约20%之间。其中藻酸盐的粘度在约2至约600mpa之间。包衣包含至少一种胶囊剂或填充剂的情况,用至少一种试剂包囊,其中缓释胶囊和选择剂以及软胶囊和胶囊剂,条件是当藻酸盐为富含G的藻酸盐时,其粘度为海藻酸盐不在约45至约420mpa / s之间的范围内。

著录项

  • 公开/公告号AR089441A1

    专利类型

  • 公开/公告日2014-08-20

    原文格式PDF

  • 申请/专利权人 BAES ERIK;WOLD IDA MARIE;

    申请/专利号AR2012P104950

  • 发明设计人

    申请日2012-12-21

  • 分类号A61K9/48;A61K47/00;A61K47/42;

  • 国家 AR

  • 入库时间 2022-08-21 15:58:52

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