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Capsules Gelatin / Alginate delayed Release comprising omega-3 fatty acids and methods and Uses of the same, method of Manufacturing, Pharmaceutical composition
Capsules Gelatin / Alginate delayed Release comprising omega-3 fatty acids and methods and Uses of the same, method of Manufacturing, Pharmaceutical composition
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机译:包含omega-3脂肪酸的明胶/海藻酸盐缓释胶囊及其方法和用途,制造方法,药物组合物
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摘要
Delayed release capsules and Methods for manufacturarlas. The Capsules comprise a capsular Coating comprises a combination of gelatin and Alginate. Where the coating comprises at least a capsular or filling Agent is Encapsulated with at least one Agent, and where the delayed release capsules are selected from soft capsules and Capsules.Claim 1: a delayed Release Capsule, which comprises a Coating comprising a combination of a capsular Gelatin Gelatin is selected between a type and a combination of a Gelatin Type A and a type B Gelatin, in which Gelatin Has a viscosity of less than about 4.2 mpau00d7segundo Bloom and / or a value of less than approximately 290 g; and Alginate in an amount ranging between 0.2% and about 20% in the weight of gelatinWhere the Alginate has a viscosity that varies between approximately 2 and approximately 600 mpau00d7segundo; where the coating comprises at least a capsular or filling Agent is Encapsulated with at least one Agent, and where the delayed Release Capsule is selected from a cu00e1psul To soft and hard Capsule, with the condition that when Alginate, alginate is rich in G,The viscosity of Alginate is not in the range of between approximately 45 and mpau00d7segundo approximately 420 mpau00d7segundo. Claim 2: The delayed Release Capsule according to claim 1, characterized in that the Capsule is selected from a sustained Release Capsule, a capsule controlled release and enteric coated Capsule.Claim 19: The delayed Release Capsule according to claim 1, characterized in that the Alginate was selected from the Potassium Alginate, Sodium Alginate, alginate, Polyethylene glycol and mixtures thereof.Claim: The delayed Release Capsule 20 according to claim 1, characterized in that the Alginate is selected from an Alginate which comprises a high fraction of manuronic acid (a residue rich in Alginate and Alginate m) comprising a fraction elev ADA (Alginate guluronic acid residues rich in g).Call 112: The delayed Release Capsule according to claim 1 or claim 59, characterized in that the Capsule is selected from a Pharmaceutical composition, Nutritional composition, a composition which is useful as a Nutritional Supplement and in Grediente for Diet.Claim: a Composition of 207 / Alginate Gelatin mixture to produce a delayed Release Capsule, which comprises a Coating comprising a combination of a capsular Gelatin Gelatin is selected between a type and a combination of a GE Latin Type A and a type B Gelatin,Where the Gelatin has a viscosity below approximately 4.2 mpau00d7segundo Bloom and / or a value of less than approximately 290 g; and Alginate in an amount ranging between 0.2% and about 20% in the weight of gelatinWhere the Alginate has a viscosity that varies between approximately 2 and approximately 600 mpau00d7segundo mpau00d7segundo; where the coating comprises at least a capsular or filling Agent is Encapsulated with at least one Agent, where the delayed Release Capsule and select entr And a Soft Capsule and a Capsule, on condition thatWhen the Alginate is an Alginate rich in G, the viscosity of Alginate is not in the range of between approximately 45 and mpau00d7segundo approximately 420 mpau00d7segundo.
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