首页> 外国专利> METHOD FOR PRODUCING PRASUGREL HYDROCHLORIDE, PRASUGREL HYDROCHLORIDE, PHARMACEUTICAL COMPOSITION, AND, USE OF A PRASUGREL HYDROCHLORIDE.

METHOD FOR PRODUCING PRASUGREL HYDROCHLORIDE, PRASUGREL HYDROCHLORIDE, PHARMACEUTICAL COMPOSITION, AND, USE OF A PRASUGREL HYDROCHLORIDE.

机译:制备普拉格瑞盐酸盐,普拉格瑞盐酸盐,药物组合物以及使用普拉格瑞盐酸盐的方法。

摘要

An object of the present invention is to provide prasugrel hydrochloride with a reduced content of CATP, and the like. In the formulae, R represents a protecting group for a hydroxyl group. A method for producing prasugrel hydrochloride represented by the above formula is provided, characterized by comprising, in step (i), controlling, at low values, the temperature during the addition, optionally dropwise, of a chlorinating agent and the reaction temperature after the addition, optionally dropwise, of the chlorinating agent.
机译:本发明的一个目的是提供具有降低的CATP含量的普拉格雷盐酸盐等。上式中,R表示羟基的保护基。提供了一种由上式表示的普拉格雷盐酸盐的制备方法,其特征在于,在步骤(i)中,将添加时的温度控制为低值,可以选择滴加氯化剂,添加后的反应温度为低值。 ,可选地滴加氯化剂。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号