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Pharmaceutical composition comprising a siRNA targeting VEGFA and method to decrease the expression of VEGFA in vivo.
Pharmaceutical composition comprising a siRNA targeting VEGFA and method to decrease the expression of VEGFA in vivo.
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机译:包含靶向VEGFA的siRNA的药物组合物和降低体内VEGFA表达的方法。
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摘要
Vascular endothelial growth factor A (VEGFA) is a chemical signal produced by cells that stimulates the growth of new blood vessels, and overexpression of VEGFA can lead to undesirable physiological conditions. Through the identification of new siRNA and modifications that improve the silencing ability of these siRNA in vivo, therapeutic compositions and methods have been invented to address the problems associated with this overexpression.
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