首页> 外国专利> Compounds derived from N - (1H - indazol - 4-yl) imidazo 1,2-a pyridin - 3 - carboxamide, inhibitors of the type III receptor tyrosine kinase; Preparation Process; Pharmaceutical Composition and use in the treatment of inflammatory diseases, cardiovascular, autoimmune disorders, fibrosis, pain Burns.

Compounds derived from N - (1H - indazol - 4-yl) imidazo 1,2-a pyridin - 3 - carboxamide, inhibitors of the type III receptor tyrosine kinase; Preparation Process; Pharmaceutical Composition and use in the treatment of inflammatory diseases, cardiovascular, autoimmune disorders, fibrosis, pain Burns.

机译:衍生自N-(1H-吲唑-4-基)咪唑并[1,2-a]吡啶-3-羧酰胺的化合物,是III型受体酪氨酸激酶的抑制剂;制备过程;药物组合物,用于治疗炎症,心血管疾病,自身免疫性疾病,纤维化,烧伤疼痛。

摘要

Compounds of Formula I: and pharmaceutically acceptable salts thereof in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification, are inhibitors of cFMS and are useful in the treatment of fibrosis, bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases, pain and burns in a mammal.
机译:式I化合物及其药学上可接受的盐,其中R1,R2,R3,R4,R5和R6具有说明书中给出的含义,是cFMS的抑制剂,可用于治疗纤维化,骨相关疾病,癌症,自身免疫性疾病,炎症性疾病,心血管疾病,疼痛和烧伤。

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