Polymorphic Compound (S) - 3 - (1 - (9H purin - 6 - ilamino) ethyl) - 8 - 2 - chlorine - fenilisoquinolin - 1 - (2H) - one of forms B J, Amorphous, Salt, hydrate or solvate thereof; mixtures of these Compounds, method for preparing the Polymorph Pharmaceutical Composition of c;; Treatment method; use for Treatment (d And a disorder mediated by PI3K.

摘要

Polymorphs of chemical compounds that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI 3 kinase activity, are described herein. Also provided herein are processes for preparing compounds, polymorphs thereof, and pharmaceutical compositions thereof.