compound or a salt, prodrug or solvate thereof, pharmaceutical composition, method for treating glk-mediated diseases, use of a compound or salt, solvate or prodrug thereof, methods for the combined treatment of obesity and diabetes and for the treatment of obesity, and a process for preparing a compound or a salt, prodrug or solvate thereof

摘要

"COMPOUND OR A SALT, PRODUCT OR SOLVATE OF THE SAME, PHARMACEUTICAL COMPOSITION, METHOD FOR THE TREATMENT OF GLK-MEDIATED DISEASES, METHOD FOR THE SAME, SOLVATOR OR PRODUCT OF THE SAME TREATMENT AND DIABETES AND FOR THE TREATMENT OF OBESITY, AND THE PROCESS FOR PREPARING A COMPOUND OR SALT, PRODUCT OR SOLVATE THEREOF ". A compound of formula (I): wherein: A is phenyl or an optionally substituted 5- or 6-membered heteroaryl ring; R¬ 1¬ and R¬ 2¬ are selected from hydrogen and methyl; provided that at least one of R¬ 1¬ and R¬ 2¬ is methyl; or a salt, prodrug or solvate thereof, are described. Their use as GLK activators, pharmaceutical compositions containing same, and processes for their preparation are also described.