首页> 外国专利> Crystalline forms I and II (R) - 1 - ethyl - 3 - 5 - fluoro - 6 - 2 - (1 - hydroxy - 3 - methyl - ethyl) pyrimidin-5-yl - 7 (tetrahydrofuran-2-ylmethyl 2 - yl) - 1h-benzimidazol-2-yl urea inhibitor Composition of gyrase; LIFE; and use for treating or reducing bacterial infection.

Crystalline forms I and II (R) - 1 - ethyl - 3 - 5 - fluoro - 6 - 2 - (1 - hydroxy - 3 - methyl - ethyl) pyrimidin-5-yl - 7 (tetrahydrofuran-2-ylmethyl 2 - yl) - 1h-benzimidazol-2-yl urea inhibitor Composition of gyrase; LIFE; and use for treating or reducing bacterial infection.

机译:晶型I和II(R)-1-乙基-3-5-氟-[6-[2-(1-羟基-3-甲基-乙基)嘧啶-5-基]-7(四氢呋喃-2-基甲基2-基)-1h-苯并咪唑-2-基]脲抑制剂促旋酶的组成;生活;并用于治疗或减少细菌感染。

摘要

The present application is directed to solid forms of compounds of formula I: and pharmaceutically acceptable salts thereof, that inhibit bacterial gyrase and/or Topo IV and pharmaceutical compositions comprising said compounds and salts. These compounds and salts are useful in treating bacterial infections.
机译:本申请涉及抑制细菌促旋酶和/或Topo IV的式I化合物及其药学上可接受的盐的固体形式,以及包含所述化合物和盐的药物组合物。这些化合物和盐可用于治疗细菌感染。

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