首页> 外国专利> Derivatives of the___ alpha__ alpha___delta___hold three______in their use in treatment on Friday

Derivatives of the___ alpha__ alpha___delta___hold three______in their use in treatment on Friday

机译:星期五在治疗中使用___ alpha __ alpha___delta_____保持3_____的衍生物

摘要

The compound of the present invention has anticancer effect and satisfies formula: (i) where R1 represents hydrogen atom and a suspension agent. Group C1-C4 alkyl or group CH2 Noh (CH2), noR1 and R2or together form a group (CH2) 3, R3 denotes a group of [alpha9595955 (C1-C4), alpha lambda kappa alpha_lambda u54e6uff0cu03acu03b6u03b9u03b4u03bfuff08C1uff5eC4uff09uff0cu03b1u03bbu03bau03bfu03beu03c5u03bau03b1u03c1u03b2u03bfu03bdu03c5u03bbu03afu03bfu03c5uff0cu03c5u03b4u03c1u03bfu03beu03c5u03b9u03bcu03b9u03bdu03bfu03bcu03b5u03b8u03c5u03bbu03afu03bfu03c5uff08C1uff5eC4uff09uff0cu03b1u03bbu03bau03c5u03bbu03bfu03c3u03bfu03c5u03bbu03c6u03bfu03bdu03c5u03bbu03afu03bfu03c5uff0cu03c4u03c1u03b9u03c6u03bbu03bfu03c5u03bfu03c1u03bfu03bcu03b5u03b8u03c5u03bbu03afu03bfu03c5uff0cu03b8u03b5u03b9u03bbu03afu03bfu03c5uff08C1uff5eC4uff09uff0cu03b1u03bbu03bau03c5u03bbu03b8u03b5u03afu03bfu03c5uff0cu9752u8272u6216u4e00u7ec4uff08CH2uff09nuff0c7r10 NRuff0cconr6r8 Nr9, or O (CH2)An identical or different alternative choice between a___________2~5 from a halogen atom, a group of (C1-C4 alkyl, _p______) u7f9fu57fau81eau7531u57fau03c5u03b4u03c1u03bfu03beu03c5u03bcu03b5u03b8u03c5u03bbu03afu03bfu03c5uff09Luff0cuff0cuff0cuff08C1uff0dC4uff09u03b1u03bbu03bau03bfu03beu03adu03bfu03c2uff0cu03bau03b1u03c1u03b2u03bfu03beu03adu03bfu03c2uff08C1uff5eC4uff09uff0cu03b1u03bbu03bau03b1u03bdu03bfu03b0u03bbu03b9u03bfu03c5uff0cu03acu03b6u03b9u03b4u03bfuff08C1uff5eC4uff09uff0cu03b1u03bbu03bau03bfu03beu03c5u03bau03b1u03c1u03b2u03bfu03bdu03c5u03bbu03afu03bfu03c5uff0cu03c5u03b4u03c1u03bfu03beu03c5u03b9u03bcu03bfu03bdu03bfu03bcu03b5u03b8u03c5u03bbu03afu03bfu03c5uff0cu5defu57fauff0cu03b1u03bbu03bau03c5u03b8u03b5u03afu03bfu03c5uff08C1uff5eC4uff09uff0cuff08C1u3002u03b1u03bbu03bau03c5u03bbu03bfu03c3u03bfu03c5u03bbu03c6u03bfu03bdu03c5u03bbu03afu03bfu03c5C4uff09uff0cu4e00u4e2au03c6u03b1u03b9u03bdu03cdu03bbu03b9u03bfuff0cu9752u8272u6216u4e00u7ec4uff08CH2uff097r10 MNRu2019uff0cconr6r8u6216Ouff08CH2uff09nr9 R5u8868u793auff0cu6216u4e00u7ec4u6216u4e00u4e2au975eu03c5u03c0u03bfu03bau03b1u03b8u03b9u03c3u03c4u03bfu03cdu03bcu03b5u03bdu03bfu03c5u03c5u03c0u03bfu03bau03b1u03b8u03b9u03c3u03c4u03bfu03cdu03bcu03b5u03bdu03bfu03c5u03b2u03b5u03bdu03b6u03bfu03b4u03b9u03bfu03beu03bfu03beu03c5u03bbu03afu03bfu03c5 A person's phi alpha__lambda_halogen, R4 and R5 are the same or different, each independently representing a hydrogen atom or a halogen or a group of water. C1 C4 alkyl, Tau93alpha959595953;_ - (CH2) nnr6r7 or nnr6r7 (CH2).
机译:本发明的化合物具有抗癌作用并且满足式:(i)其中R1代表氢原子和悬浮剂。 C1-C4烷基或CH2 Noh(CH2),noR1和R2或一起形成一个基团(CH2)3,R3表示[alpha959595 5(C1-C4) ,alpha lambda kappa alpha_lambda u54e6 uff0c u03ac u03b6 u03b9 u03b4 u03bf uff08C1 uff5eC4 uff09 uff0c u03b1 u03bb u03ba u03bf u03beu u03c5 1u03b6 u03ba u03b1 u03bd u03c5 u03bb u03af u03bf u03c5 uff0c u03c5 u03b4 u03c1 u03bf u03be u03c5 u03b9 u03bc u03b9 u03bd u03bf u03bc u03b5 u03bb u03c5 uff08C1 uff5eC4 uff09 uff0c u03b1 u03bb u03ba u03c5 u03c5 u03bbf u03c3 u03bf u03c5 u03bb u03c6 u03bf u03bd u03c5 u03bb u03af f3 u03c1 u03b9 u03c6 u03bb u03bf u03c5 u03bf u03c1 u03bf u03bc u03b5 u03b8 u03c5 u03bb u03af u03bf u03c5 uff0c u03b8 u03b5 u03b5u uff08C1 uff5eC4 uff09 uff0c u03b1 u03bb u03ba u03c5 u03bbf u03c5 uff03c5 u03af u03bfu uff09n uff0c7r10 NR uff0cconr6r8 Nr9或O(CH2)来自卤素原子的a ___________ 2〜5之间的相同或不同选择,一组(C1-C4烷基,_p______) u7f9f u57fa u81ea u7531 u57fa u03c5 u03b4 u03c1 u03bf u03be u03c5 u03bc u03b5 u03b8 u03c5 u03bb u03af u03bf u03c5 uff09L uff0c uff0c uff0c u08c1 uff0dC4 uff09 b03 u03be u03ad u03bf u03c2 uff0c u03ba u03b1 u03c1 u03bf u03c2 u03bf u03be u03ad u03bf u03c2 uff08C1 uff5eC4 uff09 uff0c u03b1 u03bb u03b u03b b03 u03bb u03b9 u03bf u03c5 uff0c u03ac u03b6 u03b9 u03b4 u03bf uff08C1 uff5eC4 uff09 uff0c u03b1 u03bb u03ba u03bfb u03beu u03c5 u03c6 u03ba b03 u03bd u03c5 u03bb u03af u03bf u03c5 uff0c u03c5 u03b4 u03c1 u03bf u03be u03c5 u03b9 u03bc u03bf u03bd u03bf u03bc u03b5 u03bb u03c5 uff0c u5def u57fa uff0c u03b1 u03bb u03ba u03c5 u03c5 uff03C5 u03af u03bf u03c5 uff08C1 uff5eC4 uff09 uff0c uff08C1 u3002 u03b1 u03b5 u03bf u03c3 u03bf u03c5 u03 bb u03c6 u03bf u03bd u03c5 u03bb u03af u03bf u03c5C4 uff09 uff0c u4e00 u4e2a u03c6 u03b1 u03b9 u03bd u03cd u03bb1 u03b9 u03 b2 u03b9 u03 u4e00 u7ec4 uff08CH2 uff097r10 MNR u2019 uff0cconr6r8 u6216O uff08CH2 uff09nr9 R5 u8868 u793a uff0c u6216 u4e00 u7ec4 u6216 u4e00 u4e2a u975e u4e2a u975e u03b8 u03b9 u03c3 u03c4 u03bf u03cd u03bc u03b5 u03bd u03bf u03c5 u03c5 u03c0 u03bf u03ba u03b1 u03b8 u03b9 u03c3 u03bb u03bf u03c5 u03b2 u03b5 u03bd u03b6 u03bf u03b4 u03b9 u03bf u03be u03bf u03bf u03b5 u03bbf u03af u03bf u03c5一个人的phi alpha相同,R和R独立地表示氢原子或卤素或一组水。 C1 C4烷基,Tau93alpha959595 953; _-(CH2)nnr6r7或nnr6r7(CH2)。

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