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RELATIONSHIPS AFFECTING Numerous PROSTAGLAND INRECPTORS TO GIVE A GENERAL ANTI-INFLAMMATORY RESPONSE

机译:影响许多前列腺炎受体给予一般抗炎反应的关系

摘要

The present invention provides compounds, that are N-alkyl-2-(1-(5-substituted-2-(3-oxo-3-(trifluoromethylsulfonamido)propyl)benzyl)pyrrolidin-2-yl)oxazole-4-carboxamide wherein the 5 substituent is selected from the group consisting of halo and alkyloxy radicals. The compound may be represented by the following formula wherein R1 is selected from the group consisting of CO2R7 and CON(R7)SO2R7 wherein R1, R2, R3, R4, and R7 are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, EP3, TP and/or EP4 receptor mediated diseases or conditions.
机译:本发明提供的化合物为N-烷基-2-(1-(5-(取代的-2-(3-氧代-3-(三氟甲基磺酰胺基)丙基)苄基)吡咯烷-2-基)恶唑-4-羧酰胺。 5个取代基选自卤素和烷氧基。该化合物可以由下式表示,其中R1选自CO2R7和CON(R7)SO2R7,其中R1,R2,R3,R4和R7如说明书中所定义。可以给予化合物以治疗DP1,FP,EP1,EP3,TP和/或EP4受体介导的疾病或病症。

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