METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PREDICTION OF KIDNEY DAMAGE AND RENAL FAILURE

摘要

The present invention relates to methods and compositions for monitoring the condition, diagnosing, predicting and determining the treatment regimen of subjects suffering from kidney damage or suspected kidney damage. In particular, the invention relates to the use of one or more assays for detecting a renal damage marker selected from the group consisting of cancer antigen CA 15-3, chemokine 18 with a C-C motive, chemokine 24 with a C-C-motive, cathepsin D, chemokine 13 with C-X-C-motif, chemokine 8 with C-C-motif, α-chain of interleukin-2 receptor, protein 3, which binds insulin-like growth factor, interleukin-11, matrix metalloproteinase-8, transforming growth factor α, IgG1 and IgG2, as diagnostic and prognostic biomarkers for damage x kidneys.