u043cu043eu043du043eu043fu0435u0433u0438u043bu0438u0440u043eu0432u0430u043du043du044bu0439 interferon alpha branched structure and a pharmaceutical composition for the preparation of these funds with activity interferon alpha

摘要

the invention belongs to the field of pharmacy and medicine, in particular to u043cu043eu043du043eu043fu0435u0433u0438u043bu0438u0440u043eu0432u0430u043du043du043eu043cu0443 u0438u043du0442u0435u0440u0444u0435u0440u043eu043du0443 various ifn - 2b u0440u0430u0437u0432u0435u0442u0432u043bu0451u043du043du043eu0439 structure, in which the u043fu043eu043bu0438u044du0442u0438 u043bu0435u043du0433u043bu0438u043au043eu043bu044f joined to a squirrel in u0444u0435u043du0438u043bu0430u043bu0430u043du0438u043du043eu0432u044bu0439 linker by u0430u043cu0438u0434u043du043eu0439 connection.the technical result of the invention is to create a u043au043eu0432u0430u043bu0435u043du0442u043du043eu0433u043e u043au043eu043du044au044eu0433u0430u0442u0430 various ifn - 2b with prolonged circulation in the bloodstream and improved characteristics of prot u0438u0432u043eu0432u0438u0440u0443u0441u043du043eu0439 activity and u0438u043cu043cu0443u043du043eu0433u0435u043du043du043eu0441u0442u0438, as well as pharmaceutical compositions for the preparation of pharmaceutical equipment, with the activity of interferon - al u044cu0444u0430.