METHODS OF REDUCING LIPOPROTEIN (A) LEVELS BY MEANS OF INTRODUCTION OF SUBTILYSIN / KEXIN-9 PROTROYKINVERTASY INHIBITOR (PCSK9)

摘要

The present invention provides methods for reducing the levels of lipoprotein (a) (Lp (a)) in patients. The methods of the present invention include the selection of a patient in whom elevated levels of serum Lp (a) are observed, and the administration to the patient of a pharmaceutical preparation containing the PCSK9 inhibitor. In some embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody, such as an example of an antibody described herein as mAb316P.