首页> 外国专利> Compounds, salts thereof, pharmaceutical compositions comprising the same, uses thereof in the preparation of medicaments for treating or preventing disorders associated with an ryr that regulates calcium channel functioning in cells and methods of synthesizing the same

Compounds, salts thereof, pharmaceutical compositions comprising the same, uses thereof in the preparation of medicaments for treating or preventing disorders associated with an ryr that regulates calcium channel functioning in cells and methods of synthesizing the same

机译:化合物,其盐,包含其的药物组合物,其在制备用于治疗或预防与调节细胞中钙通道功能的黑麦有关的疾病的药物中的用途及其合成方法

摘要

The present invention provides compounds of Formula I, (I) and salts, hydrates, solvates, complexes, and prodrugs thereof. The present invention further provides methods for synthesizing compounds of Formula I. The invention additionally provides pharmaceutical compositions comprising the compounds of Formula I and methods of using the pharmaceutical compositions of Formula I to treat and prevent disorders and diseases associated with the RyR receptors that regulate calcium channel functioning in cells.
机译:本发明提供式I,(I)的化合物及其盐,水合物,溶剂化物,复合物和前药。本发明进一步提供了合成式I化合物的方法。本发明还提供了包含式I化合物的药物组合物,以及使用式I药物组合物治疗和预防与调节钙的RyR受体相关的疾病的方法。通道在细胞中起作用。

著录项

  • 公开/公告号IL189675A

    专利类型

  • 公开/公告日2013-12-31

    原文格式PDF

  • 申请/专利号IL20080189675

  • 发明设计人

    申请日2008-02-21

  • 分类号A61K;A61P;C07D;

  • 国家 IL

  • 入库时间 2022-08-21 15:57:59

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