首页> 外国专利> Thyroid hormone receptor agonists, process for their preparation, pharmaceutical compostions comprising them and uses thereof

Thyroid hormone receptor agonists, process for their preparation, pharmaceutical compostions comprising them and uses thereof

机译:甲状腺激素受体激动剂,其制备方法,包含它们的药物组合物及其用途

摘要

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as obesity, hyperlipidemia, hypercholesterolemia and diabetes and other related disorders and diseases, and may be useful for other diseases such as NASH, atherosclerosis, cardiovascular diseases, hypothyroidism, thyroid cancer and other disorders and diseases related thereto.
机译:本文提供了式(I)的化合物:及其药学上可接受的盐,其中取代基如说明书中所公开的那些。这些化合物以及包含它们的药物组合物可用于治疗诸如肥胖,高脂血症,高胆固醇血症和糖尿病以及其他相关疾病和疾病的疾病,并且可用于诸如NASH,动脉粥样硬化,心血管疾病,甲状腺功能低下的其他疾病。 ,甲状腺癌及其他与其相关的疾病。

著录项

  • 公开/公告号IL204231A

    专利类型

  • 公开/公告日2014-04-30

    原文格式PDF

  • 申请/专利权人 F. HOFFMANN-LA ROCHE AG;

    申请/专利号IL20100204231

  • 发明设计人

    申请日2010-03-01

  • 分类号C07D;

  • 国家 IL

  • 入库时间 2022-08-21 15:57:57

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