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Pharmaceutical composition comprising 3 alpha-hydroxy-3-beta methoxymethyl- 21-(1'-imidazolyl)-5-pregnan-20-one for use in the treatment of obsessive compulsive disorder, post-traumatic stress disorder or social anxiety disorder
Pharmaceutical composition comprising 3 alpha-hydroxy-3-beta methoxymethyl- 21-(1'-imidazolyl)-5-pregnan-20-one for use in the treatment of obsessive compulsive disorder, post-traumatic stress disorder or social anxiety disorder
The present invention relates to a pharmaceutical composition, comprising 3±-hydroxy-3²-methoxymethyl-21-(1'-imidazolyl)-5a-pregnan-20-one or a pharmaceutically-acceptable salt or solvate thereof, and one or more pharmaceutically-acceptable excipients, wherein the composition provides steady state plasma levels of 3±-hydroxy-3²-methoxymethyl-21-(1'-imidazolyl)-5±-pregnan-20-one in a range of from 5 ng/mL to 500 ng/mL for a duration of from 6 h to 24 h following administration.
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机译:本发明涉及一种药物组合物,其包含3±-羟基-3 2-甲氧基甲基-21-(1'-咪唑基)-5a-pregnan-20-one或其药学上可接受的盐或溶剂化物,以及一种或多种药学上可接受的盐。 -可接受的赋形剂,其中组合物提供的稳态血浆水平为5 ng / mL至500范围内的3±-羟基-3²-甲氧基甲基-21-(1'-咪唑基)-5±-pregnan-20-one给药后ng / mL持续6小时至24小时。
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