THE ALKALI METAL TERTIARY BUTOXIDE PROMOTED, THIAZOLIUM SALT, CATALYSED SYNTHESIS OF ELECTRON DEFICIENT AMIDES

摘要

The present invention relates to the alkali metal, tertiary butoxide promoted, thiazolium salt (THZ) catalysed synthesis of electron deficient amides. The invention specifically details the redox neutral synthesis of amides from nitrophenylazides and aldehydes delivering potentially therapeutic, functionalised amides.