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IP-10 ANTIBODY DOSAGE ESCALATION REGIMENS.

机译:IP-10抗体剂量估计方案。

摘要

In certain embodiments, the present invention provides a method of treating an IP10 -related disease in a subject, comprising: (a) administering to the subject a predetermined dosage of an anti-IPIO antibody; (b) detecting the level of the anti-IPIO antibody in a sample of the subject; and (c) if the level of the anti-IPIO antibody from step (b) is below a threshold exposure level, increasing the dosage of the anti-IPIO antibody in the subject such that the IP-10 related disease in the subject is treated.
机译:在某些实施方案中,本发明提供了一种在受试者中治疗与IP10相关的疾病的方法,该方法包括:(a)向受试者施用预定剂量的抗IPIO抗体; (b)检测受试者样品中抗IPIO抗体的水平; (c)如果来自步骤(b)的抗IPIO抗体的水平低于阈值暴露水平,则增加抗IPIO抗体在受试者中的剂量,从而治疗受试者中与IP-10相关的疾病。

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