首页>
外国专利>
METHOD FOR REDUCING AMYLOID DEPOSITION, AMYLOID NEUROTOXICITY, AND MICROGLIOSIS WITH (-)-NILVADIPINE ENANTIOMER
METHOD FOR REDUCING AMYLOID DEPOSITION, AMYLOID NEUROTOXICITY, AND MICROGLIOSIS WITH (-)-NILVADIPINE ENANTIOMER
展开▼
机译:(-)-丁二酸对映体减少淀粉沉积,淀粉样神经毒性和微球藻病的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides methods for reducing A deposition, A neurotoxicity and microgliosis in an animal or human afflicted with a cerebral amyloidogenic disease, such as Alzheimer's disease (AD), by administering therapeutically effective amounts of the (R)-enantiomer of the dihydropyridine compound nilvadipine, also known as ()-nilvadipine, to the animal or human. Further provided are methods for reducing the risk of A deposition, A neurotoxicity and microgliosis in animals or humans suffering from traumatic brain injury by administering ()-nilvadipine after the traumatic brain injury and continuing treatment for a prescribed period of time thereafter.
展开▼