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PROCESS FOR PREPARING BIOACTIVE COMPLEXES OF HEDERA HELIX HERBA AND MEDICINE PRODUCT TO BE USED IN ANTI-TUMOUR THERAPY
PROCESS FOR PREPARING BIOACTIVE COMPLEXES OF HEDERA HELIX HERBA AND MEDICINE PRODUCT TO BE USED IN ANTI-TUMOUR THERAPY
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机译:制备用于抗肿瘤治疗的赫德拉草药和药物产品的生物活性复合物的方法
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摘要
The invention relates to a phytotherapeutic product, a process for preparing the same and a medicine containing the same, used in the anti-tumor therapy. According to the invention, the phytotherapeutic product contains at least 90% of total triterpene monodesmoside saponins, aglycon hederagenin, of which 70...80% alpha-hederin, usable for preparing some bioactive intermediates. According to the invention, the process consists in the liquid/liquid extraction of a triterpene glycosides complex from Hedera Helix plant, in which the alpha-hederin is first separated by a liquid/liquid extraction with ethyl acetate, followed by the separation of bisdesmosidic glycoside compounds Hederacoside C, of which there result two purified preparations, a liquid bioactive complex and an aqueous CuNa-chlorophyl extract. According to the invention, the medicine product comprises 1...2% phytotherapeutic product conditioned with pharmaceutically acceptable ingredients, suitable to the administration type.
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