Steroidal compounds as inhibitors steroid sulphatase

摘要

A compound having the formula XIII Formula XIII in which G is a group of the formula -AB in which A is linear alkylene, branched or cyclic carbon 9átomos 1 and B is a group of the formula - (CF2 ) mCF3 ​​wherein m is 0 or an integer of 1 to 9y wherein R1 is a group of the formula wherein R4 and R5 are independently selected from H, alkyl containing up to 10 decarbono atoms, cycloalkyl It comprising up to 10 carbon atoms, alkenyl containing up to 10átomos carbon and aryl containing máxido 10 carbon atoms, or combinations thereof, in laque the or each alkyl or cycloalkyl or alkenyl contain optionally one or more heteroatoms and wherein at least one of R4 and R5 is H or a pharmaceutically acceptable salt thereof.