BAG3 NUCLEOTIDE AND PROTEIN SEQUENCES TO BE USED IN RESEARCH, DIAGNOSTICS AND THERAPY FOR CELL DEATH-INVOLVING DISEASES, AND FOR MODULATION OF CELL SURVIVAL AND/OR DEATH

摘要

The present invention provides BAG3 nucleotide and protein sequences to beused in research, diagnostics and therapy for modulation of cell survivaland/or death, in particular in leukemias, other neoplasias and apoptosis-involving diseases. More particularly the invention refers to the use ofspecific antisense~-based constructs and peptide-specific polyclonal andmonoclonal antibodies in leukemias, other neoplasias and cell death- involvingdiseases.