COMPOSITIONS AND METHODS INVOLVING RESPIRATORY SYNCYTIAL VIRUS SUBGROUP B STRAIN 9320

摘要

The complete polynucleotide sequence of the human respiratory syncytial virussubgroup B strain 9320 genome is provided. Proteins encoded by thispolynucleotide sequence are also provided. Isolated or recombinant RSV (e.g.attenuated recombinant RSV), nucleic acids, and polypeptides, e.g., comprisingmutations in the attachment protein G, are also provided, as are immunogeniccompositions comprising such isolated or recombinant RSV, nucleic acids, andpolypeptides, Related methods are also described.