COMBINATION OF 3-{(2S,4S)-4-4-(3-METHYL-1-PHENYL-1H-PYRAZOL-5-YL)PIPERAZIN-1-YLPYRROLIDIN-2-YLCARBONYL}THIAZOLIDINE AND A SECOND ACTIVE AGENT AND USE THEREOF FOR PLASMA GLUCOSE CONTROL

摘要

A concomitant agent to be used simultaneously orseparately, comprising a combination of (a)3-{(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbony}thiazolidine, a salt of the compound with anorganic or inorganic and mono- or di-basic acid or a solvatethereof, and(b) at least one kind of active ingredient selected from thegroup consisting of an active ingredient of a pharmaceuticalagent selected from (i) an antidiabetic drug, (ii) a lipidlowering drug, (iii) an antihypertensive drug, (iv) atherapeutic drug for diabetic complications, (v) anantiobesity drug, (vi) an antiplatelet drug and (vii) ananticoagulant, a pharmaceutically acceptable salt thereof anda solvate thereof.