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GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONISTS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS

机译:生长激素激素受体激动剂治疗肌萎缩侧索硬化症

摘要

The present invent addresses the problem of providing a medicine for treating amyotrophic lateral sclerosis, a disease for which there is currently no effective therapeutic agent, and provides a therapeutic agent for amyotrophic lateral sclerosis that contains a growth hormone secretagogue receptor (GHS-R) agonist or a pharmaceutically acceptable salt thereof. The therapeutic agent for amyotrophic lateral sclerosis contains a GHS-R agonist such as ghrelin and is for administration to an individual who is suffering from amyotrophic lateral sclerosis and who does not exhibit severe dysphagia. The individual may be an individual who is unresponsive or insufficiently responsive to existing therapeutic agents for ALS.
机译:本发明解决了提供一种用于治疗肌萎缩性侧索硬化症的药物的问题,该疾病目前尚无有效的治疗剂,并且提供了一种包含生长激素促分泌素受体(GHS-R)激动剂的肌萎缩性侧索硬化症的治疗剂。或其药学上可接受的盐。肌萎缩性侧索硬化的治疗剂含有GHS-R激动剂,如生长素释放肽,用于患有肌萎缩性侧索硬化且没有严重吞咽困难的个体。该个体可以是对现有的ALS治疗剂无反应或反应不足的个体。

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