HELPER-DEPENDENT ADENOVIRUS VECTOR, METHOD FOR VISUALIZING MATURE OSTEOBLASTS, AND METHOD FOR PRODUCING MATURE OSTEOBLASTS

摘要

A helper-dependent adenovirus vector in which the first exon base sequence of an osteocalcin gene is substituted by a base sequence containing a reporter gene, and including at least part of the 5' upstream region of the first exon of the osteocalcin gene and at least part of the 3' downstream region of the first exon of the osteocalcin gene; and a method for visualizing and method for producing mature osteoblasts using this helper-dependent adenovirus vector.