CELL-BASED ASSAYS FOR POST-TRANSLATIONAL ENZYME ACTIVITY

摘要

Presently disclosed are cell-based methods and kits for assaying the effect of a test compound on the activity of one or more post-translational modification enzymes (e.g. kinases, methylases, etc.). The disclosed methods and kits are suitable for multiplex and/or high-throughput applications, as they are readily adaptable to assay activity of essentially any post-translational modification enzyme(s).