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USE OF THERAPEUTICALLY ACTIVE LIPIDS TOGETHER WITH METHOD OF PRODUCING ORGAN/TISSUE-SPECIFIC THERAPEUTICALLY ACTIVE LIPIDS
USE OF THERAPEUTICALLY ACTIVE LIPIDS TOGETHER WITH METHOD OF PRODUCING ORGAN/TISSUE-SPECIFIC THERAPEUTICALLY ACTIVE LIPIDS
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机译:结合使用治疗性活动脂质和生产器官/组织特定的治疗性活动脂质的方法
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摘要
The use of therapeutically active lipids for organ/tissue-specific enrichment for the treatment of inflammatory, ischemic or degenerative disorders and/or for stimulating a regeneration is arranged and developed such that the lipids are bound on application to carrier molecules for which cell-specific uptake systems in the cells of the organs and/or tissue exist. In addition, a method of producing organ/tissue-specific therapeutically active lipids for treatment of inflammatory, ischemic or degenerative disorders and/or stimulation of a regeneration, in particular for treating inflammatory liver disorders, is claimed, which is arranged and developed such that lysophosphatidylethanolamine (LysoPE) is coupled to the carboxyl group of ursodeoxycholate (UrsoDOCA) converted to an ester to give a LysoPE-DOCA compound.
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