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A METHOD FOR PRODUCING BUTANOL USING TWO-PHASE EXTRACTIVE FERMENTATION AND RECYCLABLE EXTRACTANT COMPOSITIONS
A METHOD FOR PRODUCING BUTANOL USING TWO-PHASE EXTRACTIVE FERMENTATION AND RECYCLABLE EXTRACTANT COMPOSITIONS
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机译:一种两相萃取发酵和可回收萃取剂组合物生产丁香酚的方法
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摘要
Provided herein are processes comprising providing a fermentation medium comprising a fermentable carbon source, a recombinant microorganism comprising an engineered butanol biosynthetic pathway, and butanol; contacting said fermentation medium with an extractant composition comprising an effective amount of antioxidant or antioxidant-like compound, whereby at least a portion of the butanol in the fermentation medium partitions into the extractant; recovering at least a portion of the butanol and extractant composition from the fermentation medium; recycling the extractant composition recovered in (c) one or more times in the fermentation medium; optionally adjusting the effective amount of antioxidant or antioxidant-like compound in the extractant composition, whereby the rate of oxidation or effet of oxidized products in the recycled extractant composition is substantially reduced and/or avoided such that the extractant composition may be recycled.
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