DRUG PUMP DEVICES AND NEEDLE-INSERTION MECHANISMS

摘要

In various embodiments, drug-delivery devices may utilize electrolysis pumps to push a plunger so as to deliver drug from a reservoir. The volume and/or rate of drug delivery may be monitored based on pressure measurements in the pump chamber. Pressure signatures characteristic of end-of-dose and occlusion events may be used to detect when plunger movement stops. Further, in various embodiments, drug-delivery devices for subcutaneous injections may be provided with pre-filled drug reservoirs and/or integrated needle-insertion mechanisms to increase ease of use of the devices. Certain device configurations include a needle disposed above or below the drug vial, parallel to the bottom wall of the device, with the needle-insertion mechanism placed at least partially side-by side with the vial.