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COMPOUND DIVERSIFICATION USING LATE STAGE FUNCTIONALIZATION
COMPOUND DIVERSIFICATION USING LATE STAGE FUNCTIONALIZATION
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机译:使用后期功能进行化合物多样化
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摘要
The present invention relates to methods for generating limited chemical diversity for biologically relevant lead molecules by late state functionalization, separation, and post-functionalization modification. The methods optionally include one or more screening steps. Traditional drug development has relied on the synthesis of individual compounds or the generation of large chemical libraries, but these methods have generally been fairly inefficient in obtaining drug products.
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