首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR TREATING MUSCLE-INVASIVE BLADDER CANCER, CONTAINING S100A9 AND EGFR INHIBITORS AND CISPLATIN AS ACTIVE INGREDIENTS

PHARMACEUTICAL COMPOSITION FOR TREATING MUSCLE-INVASIVE BLADDER CANCER, CONTAINING S100A9 AND EGFR INHIBITORS AND CISPLATIN AS ACTIVE INGREDIENTS

机译:包含S100A9和EGFR抑制剂及CISPLATIN作为活性成分的治疗无创膀胱癌的药物组合物

摘要

The present invention relates to a method for predicting the probability of muscle-invasive bladder cancer (MIBC) recurrence or metastasis, a method for providing information on a personalized medicine of MIBC, and a pharmaceutical composition for treating MIBC, containing S100A9 and EGFR inhibitors and cisplatin as active ingredients. According to the present invention, it is possible to accurately predict a prognosis after chemotherapy of an MIBC patient, to provide information on cisplatin sensitivity in the provision of a personalized medicine for chemotherapy of an MIBC patient, and to increase the cisplatin sensitivity of an MIBC patient by concomitantly administering S100A9 and EGFR inhibitors together with a conventional cisplatin.
机译:本发明涉及一种预测肌肉浸润性膀胱癌(MIBC)复发或转移的可能性的方法,一种提供关于MIBC的个性化药物的信息的方法以及一种用于治疗MIBC的药物组合物,其包含S100A9和EGFR抑制剂,以及顺铂为有效成分。根据本发明,有可能准确地预测MIBC患者化疗后的预后,在提供个性化的MIBC患者化疗药物中提供有关顺铂敏感性的信息,并增加MIBC患者的顺铂敏感性。通过同时使用S100A9和EGFR抑制剂以及常规的顺铂来治疗患者。

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