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2-ARYL IMIDAZO1,2-APYRIDINE-3-ACETAMIDE DERIVATIVES, PREPARATION METHODS AND USE THEREOF

机译:2-芳基咪唑并[1,2-A]吡啶-3-乙酰胺衍生物,制备方法及其用途

摘要

Disclosed are 2-arylimidazo[1,2-a]pyridine-3-acetamide derivatives represented by formula I, their tautomer, racemate or optical isomer, their pharmaceutically acceptable salt, or their solvates, wherein R 1 , R 2 , R 3 and R 4 are defined as in the specification. Preparation methods of said compounds and use of said compounds in treating and/or preventing central nervous system disease associated with TSPO functional disorder
机译:公开了由式I表示的2-芳基咪唑并[1,2-a]吡啶-3-乙酰胺衍生物,其互变异构体,外消旋体或旋光异构体,其药学上可接受的盐或它们的溶剂化物,其中R 1,R 2,R 3和R 4如说明书中所定义。所述化合物的制备方法和所述化合物在治疗和/或预防与TSPO功能障碍有关的中枢神经系统疾病中的用途

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