首页> 外国专利> METHOD FOR DETECTING METHYLATION OF THE BOWEL-CANCER-SPECIFIC METHYLATION MARKER GPM6A GENE IN ORDER TO DIAGNOSE BOWEL CANCER

METHOD FOR DETECTING METHYLATION OF THE BOWEL-CANCER-SPECIFIC METHYLATION MARKER GPM6A GENE IN ORDER TO DIAGNOSE BOWEL CANCER

机译:检测大肠癌特异性甲基化标记物GPM6A基因甲基化的方法

摘要

The present invention relates to a method for detecting methylation of the bowel-cancer-specific methylation marker GPM6A (NM_201591, glycoprotein M6A) gene in order to diagnose bowel cancer, and more specifically relates to a method for providing information for diagnosing bowel cancer by detecting the methylation of a bowel-cancer-specific marker gene that is specifically methylated in bowel cancer cells. The method for detecting methylation and a diagnostic composition, kit and nucleic-acid chip according to the present invention can be used to advantage in diagnosing bowel cancer more accurately and quickly than by normal methods as they permit bowel cancer to be diagnosed at the initial genetic transformation step and so allow early diagnosis.
机译:本发明涉及用于检测肠癌特异性甲基化标记物GPM6A(NM_201591,糖蛋白M6A)基因的甲基化以诊断肠癌的方法,更具体地,涉及通过检测来提供用于诊断肠癌的信息的方法。在肠癌细胞中特异地甲基化的肠癌特异性标记基因的甲基化。与常规方法相比,根据本发明的用于检测甲基化的方法以及诊断组合物,试剂盒和核酸芯片可以比常规方法更有利于更准确,更快速地诊断肠癌,因为它们允许在初始遗传学条件下诊断肠癌。转换步骤,因此可以及早诊断。

著录项

  • 公开/公告号EP2653547A4

    专利类型

  • 公开/公告日2014-05-07

    原文格式PDF

  • 申请/专利权人 GENOMICTREE INC.;

    申请/专利号EP20110849157

  • 发明设计人 OH TAE JEONG;AN SUNG WHAN;

    申请日2011-12-16

  • 分类号C12N15/12;C12Q1/68;G01N33/574;

  • 国家 EP

  • 入库时间 2022-08-21 15:48:16

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