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COMPOUNDS FOR TREATING CARDIAC DAMAGE AFTER ISCHAEMIA/REPERFUSION

机译:治疗局部缺血/再灌注后心脏损伤的化合物

摘要

The present invention relates to the use of an EMMPRIN inhibitor for preventing and/or treating cardiac damage arising after an ischemic process followed by reperfusion. The authors of the present invention have observed that EMMPRIN expression increases in subjects who have suffered ischemia/reperfusion, ascertaining that an EMMPRIN inhibitor is capable of reducing the cardiac damage caused after ischemia followed by reperfusion, both in vitro and in vivo .
机译:EMMPRIN抑制剂本发明涉及EMMPRIN抑制剂在预防和/或治疗缺血过程后再灌注后引起的心脏损害中的用途。本发明的作者已经观察到在患有缺血/再灌注的受试者中EMMPRIN表达增加,从而确定了EMMPRIN抑制剂能够在体外和体内减轻缺血后再灌注引起的心脏损害。

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