首页> 外国专利> COMPOSITION THAT RECOGNIZES ANTIBODIES STEMMING FROM IMMUNE-MEDIATED PERIPHERAL NEUROPATHY AND USE FOR SAID COMPOSITION

COMPOSITION THAT RECOGNIZES ANTIBODIES STEMMING FROM IMMUNE-MEDIATED PERIPHERAL NEUROPATHY AND USE FOR SAID COMPOSITION

机译:可以识别免疫介导的周围神经病变引起的抗体干AND的成分以及用于所述成分的成分

摘要

Sugar-chain-immobilized fluorescent nanoparticles that allow quick and convenient detection of ganglioside-binding autoantibodies in blood serum from immune-mediated peripheral neuropathy patients are provided, as is a use for said sugar-chain-immobilized fluorescent nanoparticles. These sugar-chain-immobilized fluorescent nanoparticles contain the following: sugar-chain ligand complexes comprising sugar chains, including ganglioside-derived sugar chains, and a prescribed linker compound that has a hydrocarbon chain or the like on the main chain thereof; and fluorescent nanoparticles that have a prescribed core-shell structure. These sugar-chain-immobilized fluorescent nanoparticles are obtained by immobilizing the abovementioned sugar chains.
机译:提供了糖链固定的荧光纳米颗粒,其允许快速和方便地检测来自免疫介导的周围神经病患者的血清中神经节苷脂结合的自身抗体,以及所述糖链固定的荧光纳米颗粒的用途。这些固定有糖链的荧光纳米粒子包含:糖链配体复合物,其包括糖链,包括神经节苷脂衍生的糖链;以及在其主链上具有烃链等的规定的连接化合物。以及具有规定的核-壳结构的荧光纳米粒子。这些固定有糖链的荧光纳米粒子是通过固定上述糖链而获得的。

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