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PREPARING AMORPHOUS MELOXICAM-β-CYCLODEXTRIN INCLUSION COMPLEX VIA SPRAY DRYING PROCESS
PREPARING AMORPHOUS MELOXICAM-β-CYCLODEXTRIN INCLUSION COMPLEX VIA SPRAY DRYING PROCESS
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机译:通过喷雾干燥工艺制备非晶态的甲氧西康-β-环糊精包合物
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摘要
The present invention relates to a spray drying process for preparing meloxicam‐β‐ cyclodextrin inclusion complex where the drug meloxicam remains stable amorphous. The process is applicable to pilot and commercial manufacturing which is advantageous compared to other technological methods. The inclusion complex obtained has desired physical chemical and biopharmaceutical properties, and can be made into product that shows superior oral absorption to the present meloxicam commercial product.
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