首页> 外国专利> METHOD FOR DETECTING BLADDER CANCER USING BLADDER CANCER-SPECIFIC EPIGENETIC MARKER GENE

METHOD FOR DETECTING BLADDER CANCER USING BLADDER CANCER-SPECIFIC EPIGENETIC MARKER GENE

机译:用膀胱癌特异性表位标记基因检测膀胱癌的方法

摘要

The present invention relates to a method for detecting methylation in the CpG island of bladder biomarker genes in order to provide information necessary in diagnosing bladder cancer or advanced stage bladder cancer; more specifically, it relates to a method for detecting a bladder cancer which is characterized in that promoter methylation of the bladder cancer-specific marker gene is confirmed in which the promoter part specifically undergoes methylation in bladder cancer transformed cells. According to the present invention, early diagnosis is possible as bladder cancer can be detected at an early transformation stage, and accurate and rapid diagnosis of bladder cancer is possible as compared to conventional methods.
机译:本发明涉及一种检测膀胱生物标志物基因的CpG岛中甲基化的方法,以提供诊断膀胱癌或晚期膀胱癌所必需的信息。更具体地,本发明涉及一种用于检测膀胱癌的方法,其特征在于,证实了膀胱癌特异性标记基因的启动子甲基化,其中启动子部分在膀胱癌转化的细胞中特异性地进行了甲基化。根据本发明,由于可以在早期转化阶段检测到膀胱癌,因此可以进行早期诊断,并且与常规方法相比,可以准确且快速地诊断膀胱癌。

著录项

  • 公开/公告号WO2014168346A1

    专利类型

  • 公开/公告日2014-10-16

    原文格式PDF

  • 申请/专利权人 GENOMICTREE INC.;

    申请/专利号WO2014KR02108

  • 发明设计人 AN SUNGWHAN;OH TAEJEONG;

    申请日2014-03-13

  • 分类号C12Q1/68;C12N15/11;G01N33/574;

  • 国家 WO

  • 入库时间 2022-08-21 15:46:29

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