首页> 外国专利> NOVEL PYRANOPYRANDIONE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESS FOR PREPARING THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FOR TREATING DISEASE DERIVED FROM ALLERGIC INFLAMMATORY RESPONSE

NOVEL PYRANOPYRANDIONE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESS FOR PREPARING THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FOR TREATING DISEASE DERIVED FROM ALLERGIC INFLAMMATORY RESPONSE

机译:新型吡喃二钱化合物或其药学上可接受的盐,制备该过程的药物和组成该药物的成分,用于治疗由过敏性炎症反应引起的疾病

摘要

The present invention relates to novel pyranopyrandione compounds or pharmaceutically acceptable salts thereof, preparing methods thereof, and pharmaceutical compositions comprising the same for treating diseases resulting from allergic inflammatory response. The novel pyranopyrandione compounds of the present invention do not exhibit toxicity in cells, suppress the eotaxin production in a dose-dependent manner, and exhibit an asthma therapy effect, and thus are widely useful in the development of more effective asthma therapeutic agents.
机译:本发明涉及新颖的吡喃并吡喃二酮化合物或其药学上可接受的盐,其制备方法以及包含其的药物组合物,其用于治疗由过敏性炎症反应引起的疾病。本发明的新型吡喃并吡喃酮化合物在细胞中不显示毒性,以剂量依赖的方式抑制嗜酸细胞活化趋化因子的产生,并显示出哮喘治疗效果,因此在开发更有效的哮喘治疗剂中广泛使用。

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