DEVELOPMENT OF SEPARATING METHOD OF (R) VINOL AND (S) VINOL USING ENANTIOMORPH PHENOMENON BETWEEN RACEMIC-VINOL AND CHIRAL BORIC ACID LIGAND AND VINOL DERIVATIVE DEVELOPMENT THROUGH INTRODUCTION OF SUBSTITUENT AT 3, 3'-POSITIONS BY SUZUKI REACTION OF SEPARATED VINOL COMPOUND

摘要

The present invention provides a chiral vinol boric acid compound with improved separability of isomers by introducing chiral boric acid ligand to a racemic-vinol derivative (+/-)-1; and a manufacturing method of a vinol derivative in which a substituent is introduced, comprising the step of preparing the chiral vinol boric acid compound.;COPYRIGHT KIPO 2014;[Reference numerals] (AA) S-form binol boric acid compound;(BB) R-form binol boric acid compound