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Preparation methods of anticancer drug for photodynamic therapy to tumor cell using photocatalytic metal oxide

机译:光催化金属氧化物对肿瘤细胞进行光动力治疗的抗癌药物的制备方法

摘要

the present invention comprises: (a) the chain end of polyethylene oxide having an anhydride group and the synthesis , (b ) this Fallick acid , doxorubicin , seulpon amide drugs , and adenosine and prepared by reaction of the polymeric drug , or polyethylene oxide- block copolymer and combining the poly- maleic acid , (c) (b) a polymer prepared from the drug itself or a mixture thereof , wherein use producing a butanol or ethanol , or THF / water, the titanium dioxide particles in the mixed solution in the nano-scale , and relates to a method for stabilization . According to the present invention , having an anti-cancer effect , a wide-area chemical treatment of cancer additionally producing the nanoparticles of the efficacy and expected to provide a new electric field on this because it can be used in drug delivery systems (drug delivery system) is .
机译:本发明包括:(a)具有酸酐基团的聚环氧乙烷的链端和合成,(b)该法酸,阿霉素,Seulpon酰胺药物和腺苷,并通过聚合药物或聚环氧乙烷的反应制备。 (c)(b)由药物本身或其混合物制得的聚合物,其中使用丁醇或乙醇或THF /水生产时,混合溶液中的二氧化钛颗粒纳米级,并且涉及一种稳定化的方法。根据本发明,具有抗癌作用,对癌症的广域化学治疗还产生了功效的纳米颗粒,并且由于其可用于药物输送系统(药物输送)而有望提供新的电场。系统)是。

著录项

  • 公开/公告号KR101330747B1

    专利类型

  • 公开/公告日2013-11-18

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20110089745

  • 发明设计人 이상필;

    申请日2011-09-05

  • 分类号C07D475/04;C07D309/14;A61K31/4162;A61K31/4985;

  • 国家 KR

  • 入库时间 2022-08-21 15:44:20

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