Nano ion-complex for photodynamic theraphy comprising hydrophile cationic polymer photosensitizer derivatives and anionic polysaccharide quencher derivatives

摘要

PURPOSE: A nanoion complex containing a hydrophilic cationic polymer photosensitizer derivative and an anionic polysaccharide quencher derivative for photodynamic therapy is provided to enhance accumulation rate to a cancer tissue and to generate single oxygen or free radical. CONSTITUTION: A nanoion complex for photodynamic therapy contains a hydrophilic cationic polymer photosensitizer derivative and an anionic polysaccharide quencher derivative. The hydrophilic cationic polymer photosensitizer derivative is a copolymer containing a cationic polymer conjugated with a photosensitizer.